Our admissions team is available now, 24/7
Complete guide · Mental states and traits

Loneliness and social isolationTheir effect on mental and physical health, and how to overcome them

Reviewed by: Dr. Mahmoud El-Sawy Last updated: October 1, 2026 5 min read
The short answer

Loneliness is a painful feeling that your relationships are fewer or weaker than you need, and you can feel it in the middle of a crowd. Isolation, on the other hand, is a lack of actual contact with others. The World Health Organization estimates that about 1 in 6 people worldwide experience loneliness, and links it to about 871,000 deaths a year. It is linked to depression, anxiety and heart disease, and may push people toward substance use. This state can be changed with small, deliberate steps.

  • Loneliness is a signal like hunger, telling you that you need connection; it does not indicate a flaw in your personality.
  • Long-term loneliness makes the mind more sensitive to rejection, which increases withdrawal.
  • The quality of relationships matters more than their number.

What is the difference between loneliness and isolation?

You can be in a house full of people, or in a group of friends on your phone, and still feel that no one truly sees you. Loneliness is a sense of distance between you and those around you, however many they are.

Loneliness versus social isolation
LonelinessSocial isolation
An internal feelingA measurable state: few meetings and little contact
Can happen in the middle of a crowdSomeone can live it without feeling lonely
Relates to the quality of relationshipsRelates to the number and frequency of relationships
Psychologically painful by natureMay be a comfortable choice for some people

Both affect health, and the most harmful is when they come together: a person with little contact who suffers because of it.

The effect of loneliness on health

The World Health Organization Commission on Social Connection issued a global report in 2025, estimating that loneliness is linked to about 100 deaths every hour worldwide. An analysis of studies covering hundreds of thousands of people found that loneliness and isolation raise the risk of early death to a degree comparable to known risk factors. Its effects include:

  • Increased risk of depression and anxiety.
  • Disturbed and poorer-quality sleep.
  • Higher stress hormones and levels of inflammation in the body.
  • Increased risk of heart disease and strokes.
  • Declining memory and increased risk of dementia in older adults.
  • Increased risk of suicidal thoughts.
  • Turning to alcohol, drugs or screens to fill the void.

Why does loneliness feed itself?

Researchers explain that long-term loneliness puts the brain in a state of social alert, making it more sensitive to any sign of rejection, and a self-feeding cycle forms:

  1. 1
    Feeling lonely

    A sense of distance from others or of not being understood.

  2. 2
    Sensitivity to rejection

    The mind anticipates rejection and interprets neutral situations as coldness.

  3. 3
    Negative expectations

    “Nobody wants to talk to me,” “They'll be bothered if I call.”

  4. 4
    Withdrawal

    Avoiding invitations and contact to avoid the expected rejection.

  5. 5
    Deeper loneliness

    Less contact confirms the first idea, and the cycle repeats.

Circular infographic of the vicious cycle in loneliness: feeling lonely → sensitivity to rejection → negative expectations → withdrawal → deeper loneliness
The loneliness cycle: how sensitivity to rejection leads to more withdrawal

Loneliness and addiction

Loneliness is one of the strongest drivers of substance use and relapse: alcohol and drugs give a temporary feeling of relief or of belonging to a group that uses, then deepen isolation over time. Many people in recovery say that the loneliness after stopping was harder than the physical withdrawal. This is why recovery programs focus on building a support network and therapy groups, which are an essential part of follow-up and relapse prevention.

How do you overcome feeling lonely?

  1. Start small: a message to an old friend, a call to a relative, or a greeting to a neighbor. Do not expect a deep relationship from the first step.
  2. Pay attention to your thoughts: when you tell yourself “nobody cares,” ask: what is the evidence? What is the other explanation? Studies have shown that working on these thoughts is one of the most successful ways to ease loneliness.
  3. Join a regular activity: a team sport, volunteering, a course, or a religious activity; repetition builds familiarity.
  4. Help others: volunteering and helping others reduce loneliness and give meaning.
  5. Cut back on comparison on social media, and use it for real connection, not just watching.
  6. Look after the basics: sleep, movement and sunlight improve mood and make connecting easier.
  7. Ask for help if the loneliness comes with persistent sadness or social anxiety that keeps you from approaching people.

When do you need a specialist?

If loneliness continues with sadness and loss of pleasure for more than two weeks, or anxiety keeps you from approaching people as in social phobia, or you have started to rely on alcohol, sedatives or drugs to fill the void, or thoughts about death have crossed your mind, a psychological assessment is an important step. If you are in danger now, contact the mental health support line 16328, and you can find more on the page about suicidal thoughts.

Loneliness that turned into despair or suicidal thoughts? Get help now

  • Talking about wanting to die or that no one would miss them
  • Severe hopelessness and a feeling that no one cares and there is no way out
  • A sudden, complete break from family and friends, or saying goodbye to them
  • Obvious neglect of eating, hygiene or medication, especially in older adults who live alone
  • Increased drinking or substance use to fill the void

Do not leave the person alone; visit them or stay with them on the phone, ask calmly and openly about their thoughts and listen without blame, since asking does not plant the idea, it opens the door to help. Call an ambulance on 123 or take them to the nearest emergency room if they are in danger, or call the mental health support line 16328, available around the clock, and keep medication and anything they could use to harm themselves out of their reach.

Ambulance 123 Mental health support line 16328
Frequently asked questions

Frequently asked questions about loneliness and isolation

Didn’t find your answer?

Ask an advisor directly. The reply is confidential and carries no commitment.

Ask on WhatsApp
What is the difference between loneliness and isolation?

Loneliness is an internal feeling of lacking relationships that can occur in the middle of a crowd, while isolation is an actual lack of contact with others.

What is the effect of loneliness on health?

It is linked to depression, anxiety, sleep disturbance, heart disease, declining memory and early death.

Is loneliness a mental illness?

It is not an illness in itself, but it is a painful feeling that can lead to depression, anxiety and substance use if it goes on.

How do I overcome feeling lonely?

With small, regular steps toward connection, reviewing negative thoughts about others, joining regular activities, and helping others.

Why do I feel lonely in the middle of people?

Because loneliness is about the quality of relationships and the sense of being understood and accepted, not about the number of people around you.

Does loneliness cause addiction?

It can be a strong driver of substance use and relapse, because substances give temporary relief and then deepen isolation.

How many people experience loneliness?

The World Health Organization estimates that about 1 in 6 people worldwide experience loneliness.

Need help with loneliness and social isolation?

Your information is confidential and is not shared with anyone

Call WhatsApp Consultation