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Mother's Guide

Drugs and PregnancyHow does a substance reach the fetus, what happens to the newborn, and how can a mother ask for help without fear?

Reviewed by: Dr. Mahmoud El-Sawy Last updated: October 4, 2026 5 min read
The short answer

Drugs and pregnancy are a dangerous combination because most substances cross the placenta and reach the fetus, according to the US National Institute on Drug Abuse, which states that smoking tobacco or cannabis, or taking opioid painkillers or drugs during pregnancy, is linked to a two- to three-fold increase in the risk of stillbirth. The baby may be born with withdrawal symptoms called neonatal abstinence syndrome. Even so, stopping opioids suddenly during pregnancy is not advised; instead, medication treatment under medical supervision is.

  • Seeking treatment during pregnancy is courage, not shame.
  • The doctor needs to know everything you take so they can protect you and your baby.
  • Do not start or stop any medicine or substance without a doctor.

"I found out I'm pregnant, and I'm afraid to tell the doctor I'm taking something." This fear is understandable, but it is the most dangerous part of the story. A pregnant woman who hides what she takes deprives herself and her baby of care that could change the whole outcome. Drugs and pregnancy is a subject that needs frankness and compassion together.

How do drugs affect pregnancy and the fetus?

The US National Institute on Drug Abuse explains that many substances cross the placenta easily, so what a pregnant woman takes reaches the fetus as well. The institute estimates that about 5% of pregnant women use one or more addictive substances, and that the effect varies with the substance, the amount, how long it was used, how well the mother's body breaks it down, and whether the baby was born on time or early.

Among the effects the institute lists for some substances, such as cannabis, cocaine, and crystal meth (shabu), are birth defects, low birth weight, premature birth, smaller head circumference, and an increased risk of sudden infant death. It notes that babies whose mothers drank alcohol and smoked after the first trimester face about a 12-fold higher risk of sudden death than other babies.

Drugs, pregnancy, and the risk of stillbirth

The institute presents figures from a study published in 2013 on the risk of stillbirth:

  • Smoking tobacco: a risk 1.8 to 2.8 times higher, rising with heavier smoking.
  • Cannabis: a risk 2.3 times higher.
  • Any stimulants, cannabis, or opioid painkillers: a risk 2.2 times higher.
  • Secondhand smoke: a risk 2.1 times higher.

The effect of each substance on pregnancy

Drugs and pregnancy: substance by substance
Opioids (tramadol and heroin)HashishStimulants (crystal meth and cocaine)
On the pregnancyAbrupt withdrawal is linked to higher relapse and worse outcomesLinked to low birth weightHigh blood pressure, placental abruption, and premature birth
On the newbornNeonatal abstinence syndromeTremors and sharp crying in some newbornsLow weight, small head, and irritability
In the long termNeeds growth monitoringAssociations with attention and memory problems that need more researchAttention and emotional problems in some studies
RecommendationMedication treatment under supervision rather than abrupt stoppingStopping with supportStopping, with monitoring of the pregnancy and blood pressure
Infographic on drugs and pregnancy, substance by substance: on the pregnancy, on the newborn, in the long term, recommendation
A simplified comparison of the effect of the best-known substances on the pregnancy and the newborn.

As for alcohol, the US National Institute on Alcohol Abuse and Alcoholism says that pregnant women and those who might be pregnant should avoid it completely. The National Institute on Drug Abuse warns against any vaping product during pregnancy, whatever its substance, citing the US Food and Drug Administration.

Neonatal abstinence syndrome: drug withdrawal in the newborn

When the mother becomes accustomed to a substance such as opioids, the fetus's body becomes accustomed to it too, and when the baby is born it is cut off suddenly. According to the National Institute on Drug Abuse, symptoms may appear right at birth or up to 14 days later, and include persistent sharp crying, tremors, poor feeding, vomiting and diarrhea, sneezing and stuffy nose, little sleep, and slow weight gain, and they can reach seizures.

The syndrome is not limited to opioids; the institute notes that alcohol, barbiturates, benzodiazepines, and caffeine can also cause withdrawal symptoms in the newborn. A StatPearls review explains that the baby is monitored in the hospital and treated first with supportive care, and with medication when needed.

Opioids during pregnancy: why is stopping suddenly not advised?

Stopping immediately may seem the obvious ethical solution, but the American College of Obstetricians and Gynecologists, in its Committee Opinion No. 711, recommends medication treatment with opioid agonists as the recommended treatment for a pregnant woman with opioid use disorder, and as preferable to supervised withdrawal, because withdrawal is linked to high relapse rates that lead to worse outcomes. The right medicine and its dose are determined by the doctor, and in heroin withdrawal you can find why stopping suddenly is not advised during pregnancy.

Drugs and breastfeeding

The National Institute on Drug Abuse states that THC can reach breast milk and accumulate in it with regular use, so cannabis is not advised during breastfeeding. It varies between medicines: some are compatible with breastfeeding and some have an unknown effect, and the decision belongs to the pediatrician and the treating doctor together.

How can a pregnant woman get help?

  1. Tell your follow-up doctor the whole truth; she needs it for your safety.
  2. Ask for an assessment from a psychiatrist or addiction doctor, especially if you take opioids or sedatives.
  3. Call the hotline of the Fund for Drug Control and Treatment of Addiction on 16023; its services are free and confidential.
  4. After delivery, monitor your mental health closely; the early period is hard, and postpartum depression may appear.

Eradah's residential program is for men only, but the first consultation is free and confidential for women too, and the team helps you find the place suited to your situation. You can find more in the guide to addiction in women.

Frequently asked questions

Frequently asked questions about drugs and pregnancy

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How do drugs affect the fetus?

Most substances cross the placenta and may be linked to low weight, premature birth, a small head, and birth defects, and to a doubling of the risk of stillbirth, in addition to withdrawal symptoms in the newborn.

Does cannabis affect pregnancy?

The US National Institute on Drug Abuse links it to low birth weight and to about a 2.3-fold higher risk of stillbirth, and it is not advised during pregnancy or breastfeeding.

Can a pregnant woman stop tramadol suddenly?

This is not advised. The American College of Obstetricians and Gynecologists recommends medication treatment under medical supervision rather than withdrawal, because withdrawal is linked to higher relapse and worse outcomes.

What is neonatal abstinence syndrome?

Withdrawal symptoms that appear in a newborn after being cut off from a substance it became accustomed to in the womb, such as sharp crying, tremors, poor feeding, and vomiting, and they may appear up to 14 days after birth.

Do drugs and pregnancy cause birth defects?

Some substances are linked to birth defects, and this varies with the substance and the timing of exposure, which is why a pregnant woman needs careful medical follow-up.

Does Eradah admit pregnant women?

Eradah's residential program is for men, but the first consultation is free and confidential for women, and the team helps them find the right place.

Medical reviewDr. Mahmoud El-Sawy, Consultant Psychiatrist and Addiction Specialist

This page was written by Eradah's editorial team and reviewed by a specialist doctor under the medical review policy. Last reviewed: October 4, 2026. The content is for awareness and does not replace a doctor's consultation.

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