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Awareness guide

Drug vapesWhat else goes into an e-cigarette besides nicotine, and why is it more dangerous than it looks?

Reviewed by: Dr. Mahmoud El-Sawy Last updated: October 4, 2026 6-minute read
The short answer

A drug vape is an e-cigarette whose tank, or "pod", is filled with a liquid containing THC, the active substance in hashish, or synthetic cannabinoids from the Strox family, instead of nicotine. The danger is that the liquid is often of unknown composition. In a study of e-cigarettes confiscated from English schools in 2025, 17.4% of the samples contained synthetic cannabinoids, while real THC was rare. The US Centers for Disease Control and Prevention also linked most cases of the well-known lung injury EVALI to THC liquids from informal sources.

  • The look of the device does not reveal what is inside, and the smell may be fruity or absent.
  • Synthetic cannabinoids in a vape can cause seizures and psychosis after just a few puffs.
  • If someone loses consciousness or has a seizure after vaping, call an ambulance (123).

"It's just a strawberry vape, Mom." That sentence may be true, and it may not. A device that looks like a pen or a flash drive can hold nicotine, or it can hold a liquid containing cannabis or a synthetic substance whose makeup even the seller does not know. That is where the term drug vapes comes from, which parents in Egypt have begun to hear.

What is a drug vape?

As the US National Institute on Drug Abuse explains, an e-cigarette is a battery-powered device with four parts: a tank or "pod" holding a liquid, a heating element, a battery, and a mouthpiece. When the person inhales, the liquid heats up and turns into an aerosol that is breathed in. The institute adds that these devices can look like pens or USB drives, are easy to hide, and do not leave the usual smell of cigarettes.

A drug vape is the same device, but the liquid in it is not nicotine. The two most common contents are THC oils or liquids extracted from cannabis, and liquids with synthetic cannabinoids from the family of Strox and "chemical" added. Nicotine e-cigarettes have their own guide on the page about smoking and nicotine addiction.

Types of drug vapes: what goes into the liquid?

The difference between what may be found in vape liquid
Nicotine vapeCannabis (THC) vapeSynthetic cannabinoid vape
SubstanceNicotine and flavoringsTHC extracted from cannabisLaboratory compounds that imitate THC at far greater strength
Does the user know what they are taking?UsuallySometimes, and it is often adulteratedRarely, and it may be sold as "hashish"
Main riskNicotine addictionPsychosis and anxiety, and lung injury with additivesSeizures, psychosis and loss of consciousness
Does it show up on a drug test?Not usually tested forShows up on a cannabis testMuch of it does not show up on the usual test strips

The problem is that the eye cannot tell the three apart. The devices look alike, the liquids are colored and scented, and an adulterated bottle carries nothing on its label that tells the truth.

What have studies found in drug vape liquids?

In a study published in the journal Addiction in 2025, British researchers analyzed e-cigarettes and liquids confiscated by teachers from 27 secondary schools in England. They found synthetic cannabinoids in 17.4% of all samples, and in schools making up 77.8% of those taking part. Most were in refillable devices and liquid bottles, while only a few samples contained THC.

This finding matters because the study began after reports of students collapsing unconscious at school after using a vape believed to be "hashish". In other words, many young people think they are smoking cannabis when they are in fact inhaling a stronger and more dangerous laboratory-made substance.

In France, a medical report published in 2021 described a 16-year-old who developed symptoms resembling an epileptic seizure minutes after using a friend's e-cigarette. The synthetic cannabinoid 5F-ADB was found in the liquid and in his blood.

Vaping-associated lung injury (EVALI)

In 2019 the United States saw a wave of acute lung injuries among e-cigarette users, named EVALI. According to the US Centers for Disease Control and Prevention's final update in February 2020, 2,807 cases needed hospitalization or ended in death, including 68 confirmed deaths.

The CDC concluded that vaping products containing THC, especially from informal sources such as friends and dealers, were linked to most cases, and that vitamin E acetate, added to some THC liquids, was strongly linked to the injuries, though other chemicals were not ruled out. The lesson is that an adulterated liquid can harm the lungs, not only the brain.

Risks of drug vapes

Unknown composition

Neither the user nor, sometimes, the seller knows what is in the liquid or how concentrated it is.

Psychosis and panic attacks

Synthetic cannabinoids and concentrated THC can cause paranoia, hallucinations and severe anxiety.

Seizures

Seizure-like episodes have been recorded after a few puffs of a vape containing synthetic cannabinoids.

Lung injury

Additives such as vitamin E acetate have been linked to severe lung injury.

Easy repeat use

The device is in a pocket all day, so use becomes frequent and leads to dependence.

Sharing the device

Many cases began with a puff from a friend's device without knowing what was in it.

Infographic of drug vape risks: unknown composition, psychosis and panic attacks, seizures, lung injury, easy repeat use, sharing the device
Six risks that make drug vapes more dangerous than their simple look suggests.

The National Institute on Drug Abuse notes that THC concentration in seized cannabis products rose about fourfold between 1995 and 2022, and that higher concentrations are linked to a greater chance that use will develop into cannabis use disorder. You can find details in the guide to hashish.

How can a family tell whether a vape contains drugs?

  • Red eyes, or unusual laughter, drowsiness or confusion after using the device.
  • A device that is carefully hidden or borrowed from one particular "friend".
  • Cartridges or liquid bottles with no clear labels, or with strange names.
  • A sudden change in sleep, schoolwork and friends.
  • A panic attack, suspicion, a seizure or fainting after vaping, which is a danger sign.

A single sign does not mean your child is using drugs. A calm conversation works better than searching their things and confronting them harshly, as the guide to signs of drug use explains.

What should you do if someone becomes unwell after a drug vape?

You will find detailed first-aid steps in the guide to acute drug poisoning.

How is someone who is used to drug vapes treated?

Treatment begins with an assessment of what was actually being used, then treatment of any withdrawal symptoms, cognitive behavioral therapy to change the hand-and-device habit, and treatment of any accompanying anxiety or depression. Many young people need outpatient treatment with family support, while someone who has had repeated psychotic episodes or seizures needs a more careful assessment and may need a short stay.

Frequently asked questions

Frequently asked questions about drug vapes

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What is a drug vape?

An e-cigarette filled with a liquid containing THC from cannabis, or synthetic cannabinoids such as Strox, instead of nicotine.

Are there cannabis vapes?

Yes, THC liquids and oils exist that are smoked in e-cigarettes, but much of what is sold as cannabis may contain synthetic cannabinoids, as a study of English school samples found.

Are drug vapes milder than regular hashish?

No. The liquid may be more concentrated or contain a far stronger synthetic cannabinoid, and seizures and loss of consciousness have been recorded after just a few puffs.

Do drug vapes show up in a urine test?

THC vapes usually show up on a cannabis test, but many types of synthetic cannabinoids are not picked up by the usual strips and need specialized tests.

How do I know if a vape contains drugs?

You cannot tell from the look or smell of the device, but a change in behavior after using it, unlabeled liquid bottles, and signs such as red eyes and confusion call for a conversation and an assessment.

What is EVALI?

An acute lung injury linked to e-cigarettes, which the US Centers for Disease Control and Prevention tied to informal THC liquids and to vitamin E acetate added to them.

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